Prize poem
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Eureka moments
Email us your eureka moments to info@theyoungdarwinian.com, and we will put them in this post.
1. Tony Campbell
Tony Campbell had a eureka moment in the Marine Biological Association lab at Plymouth in 1973. He was trying to extract a bioluminescent protein from the hydroid Obelia geniculata. It just was not working. By 9 pm he was about to give up. But he decided to carry out one final experiment, by extracting the hydroid in different pH’s. Eureka! It worked. The oscilloscope screen used to detect the light from his extract was wiped out. He jumped around in delight! Bioluminescence really did have the wow factor! This experiment changed his life, and career, for ever! He realised that a flash was better than a glow. This eureka moment, when no one else was there, led him to develop a way of replacing radioactive antibody and DNA labels with a chemical that emitted light. This technique is now used in several hundred million clinical tests per year world wide. He also realised he could use the DNA from these bioluminescent animals to light up chemical processes in living cells and whole organisms, such as calcium signals that control the whole of life. This has revolutionised biomedical research and drug discovery. His eureka moment has led to the creation of three individual billion dollar markets, with jobs for thousands of scientists. It also inspired him to set up The Darwin Centre in Wales, and The Young Darwinian.
Curiosity inspires, but discovery reveals.
Download these articles by clicking on the link
1. Regulation of Integrin Alpha 6 in Relation to Myelination: An Exploration of Peripheral Nervous System Repair
by Rachel Gump, a biology student at Callington Community College, Cornwall, UK
Download her project here Gump 2018 final
2. Star trek science comes alive
By Stephanie B Matthews
3. Curiosity inspires, discovery reveals
By Anthony Campbell
ART 2017_2
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This is an example of DNA sings, by converting two protein sequences into music
This has been done by setting a note for each amino acid in the protein sequences
Aequorin and obelin are both bioluminescent proteins that produce light when they bind calcium
DNA sings and so DNA makes music
Why not try to make DNA sing, and convert your own DNA into music. This is quite easy using software available in most schools. Proteins use up to 20 amino acids to form their sequence, and, of course, DNA uses triplets of four bases Adenine (A), Guanine (G), Cytosine (C), and Thymine (T) to code for these. So, in C major, you give each amino acid a note around middle C. I decided to use the low notes for basic amino acids like lysine and arginine, and high notes for acidic amino acids like aspartic acid and glutamic acid. I then typed these in using Sibelius, that then puts the notes on a stave. You can then play this with any instrument. I used two calcium binding bioluminescent proteins I have studied for forty years. The result is in the picture. Listen to the Wav file. When you hear high notes, this is where the calcium binds. You can then use software like Cubase or Garage band to add an accompaniment.
Have a go, and email us your results. We will put them up on the web site. email us at info@theyoungdarwinian.com
Good luck.
Tony
Professor Anthony K Campbell
Editor in Chief
The Young Darwinian
info@theyoungdarwinian.com
27/03/2017

This video shows an amazing flashing jelly fish, and the tiny heart of a water flea, Daphnia. Daphnia are found in ponds throughout the world and are great for school projects.